University of Tehran Iranian Economic Review 1026-6542 Articles in Press 2026 05 12 Health-Economy Uncertainty, Institutional Quality and Economic Growth in Iran: A Time-Varying Parameter Analysis 106864 10.22059/ier.2026.408866.1008378 EN Ramin Amani Department of Economic Development and Planning, Faculty of Management and Economics, Tarbiat Modares University, Tehran, Iran. Abbas Assari Arani Department of Economic Development and Planning, Faculty of Management and Economics, Tarbiat Modares University, Tehran, Iran. Almas Heshmati Visiting Professor of Economics, University of Economics Ho Chi Minh city, Vietnam. Lotfali Agheli Institute of Economic Research, Tarbiat Modares University, Tehran, Iran. Journal Article 2025 12 26 This study examines how health economy uncertainty and institutional quality jointly affect long run economic growth in Iran (1989–2024). Using an augmented Solow–Swan framework, we construct a novel health economy uncertainty index from 24 indicators (mortality, access to services, public health, health expenditures) and combine it with an institutional quality index from ICRG components. A time varying parameter OLS (TVP OLS) model with a Kalman filter allows all coefficients to evolve smoothly. Results show that health economy uncertainty has a negative and statistically significant effect on real output, while institutional quality exerts a positive and robust impact. The interaction term between the two is also negative, indicating that stronger institutions mitigate but do not neutralise the adverse effect of uncertainty. Traditional supply side drivers—labour and fixed capital—retain their expected positive contributions. The findings imply that Iran’s growth depends on structural fundamentals, health sector stability, and institutional quality, calling for integrated reforms that simultaneously reduce health uncertainty and strengthen institutions.